Variation of food intake and body weight with estrous cycle, ovariectomy, and estradiol benzoate treatment in hamsters (Mesocricetus auratus).

Abstract

Food intake and body weight of hamsters fluctuated systematically with the estrous cycle. Food intake and body weight were lowest when elevated endogenous estrogen levels were expected. Ovariectomized hamsters gained a significant amount of body weight compared with sham-operated animals. Replacement therapy with estradioal benzoate reduced the body weight and food intake of ovariectomized animals relative to oil-injected, ovariectomized control animals. The results are compared with similar data from rats and support the concept that in females of both species estradiol operates to regulate food intake and body weight.

• Authors: L P Morin, A S Fleming
• Journal: Journal of comparative and physiological psychology (J Comp Physiol Psychol) Vol. 92 Issue 1 Pg. 1-6 (Feb 1978) ISSN: 0021-9940 [Print] United States
• PMID: 564357 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)

Chemical References

• Estradiol

Topics

• Animals
• Body Weight (drug effects)
• Castration
• Cricetinae
• Estradiol (pharmacology)
• Estrus
• Feeding Behavior (drug effects)
• Female
• Humans
• Pregnancy
• Time Factors