| Abstract | Experiments on white mice demonstrated that the appearance of extrapyramidal disturbances depends upon the scheme of haloperidol administration. A long-term use of the preparation leads to development of habituation, while its cessation--to symptoms similar to withdrawal. The development of extrapyramidal disturbances does not increase the antagonism of haloperidol in relation to phenamine, but distinctly increases and prolongs the activizing action of the blood serum of schizophrenic patients on the behaviour of animals. |
| Authors | Z M Bobritskaia, L G Gorbatko, N M Litvinova, G V Stoliarov |
| Journal | Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952)
(Zh Nevropatol Psikhiatr Im S S Korsakova)
Vol. 77
Issue 4
Pg. 591-5
( 1977)
ISSN: 0044-4588 USSR |
| Vernacular Title | Vliianie ékstrapirimidnykh narusheniĭ, vyzvannykh galoperidolom, na fenaminvovye stereotipii i éffekty syvorotke krovi bol'nykh shizofrenieĭ (éksperimental'noe issledovanie) |
| PMID | 559400
(Publication Type: English Abstract, Journal Article)
|
| Chemical References |
- Immune Sera
- Amphetamine
- Haloperidol
|
| Topics |
- Amphetamine
(antagonists & inhibitors)
- Animals
- Basal Ganglia Diseases
(chemically induced)
- Behavior
- Behavior, Animal
- Haloperidol
- Humans
- Immune Sera
(pharmacology)
- Rats
- Schizophrenia
(blood)
- Stereotyped Behavior
|
