HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Left ventricular dysfunction after intravenous tartar emetic.

Abstract
Left ventricular dysfunction had been reported in many patients suffering from schistosomal cor pulmonale. The nocuous agents affecting the left ventricle have not been defined. Antischistosomal therapy is suspected to contribute in the adverse effects on the myocardium, particularly antimonials and niridazole. In this study, the left ventricular performance was studied in 29 patients suffering from schistosomiasis before and 30 min after i.v. therapeutic dose of a tartar emetic. After the injection, the PEPI and PEPI/LVETI were increased, the LVETI was abbreviated, EF. was reduced, the LVEDP was raised, the peak dp/dt and the Vmax were reduced. Toxic effects of the T.E. on the myocardium and diminished contractility of the left ventricle were presumed to be caused by T.E. Other factors adversely affecting the myocardium in patients suffering from schistosomiasis cannot be excluded.
AuthorsM H Badr, G M Zayadi, F K Harras
JournalEgyptian journal of bilharziasis (Egypt J Bilharz) Vol. 5 Issue 1-2 Pg. 9-18 ( 1978) ISSN: 0301-8849 [Print] Egypt
PMID555759 (Publication Type: Journal Article)
Chemical References
  • Antimony
  • Antimony Potassium Tartrate
Topics
  • Adolescent
  • Adult
  • Antimony (adverse effects)
  • Antimony Potassium Tartrate (adverse effects, therapeutic use)
  • Heart Diseases (chemically induced, physiopathology)
  • Humans
  • Injections, Intravenous
  • Pulmonary Heart Disease (drug therapy)
  • Schistosomiasis (drug therapy, physiopathology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: