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Inhibition of ribonucleotide reductase, DNA synthesis, and L1210 leukemia by guanazole.

AuthorsR W Brockman, S Shaddix, W R Laster Jr, F M Schabel Jr
JournalCancer research (Cancer Res) Vol. 30 Issue 9 Pg. 2358-68 (Sep 1970) ISSN: 0008-5472 [Print] United States
PMID5475481 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Carbon Isotopes
  • DNA, Neoplasm
  • Formates
  • Hypoxanthines
  • Neoplasm Proteins
  • RNA, Neoplasm
  • Tritium
  • Oxidoreductases
  • Leucine
  • Adenine
  • Azaguanine
  • Thymidine
  • Uridine
  • Hydroxyurea
Topics
  • Adenine (metabolism)
  • Animals
  • Azaguanine (administration & dosage, pharmacology)
  • Carbon Isotopes
  • Carcinoma, Squamous Cell (metabolism)
  • Culture Techniques
  • DNA, Neoplasm (biosynthesis)
  • Female
  • Formates (metabolism)
  • Hydroxyurea (pharmacology)
  • Hypoxanthines (metabolism)
  • Leucine (metabolism)
  • Leukemia L1210 (drug therapy, enzymology, metabolism)
  • Male
  • Mice
  • Neoplasm Proteins (biosynthesis)
  • Oxidoreductases (antagonists & inhibitors)
  • RNA, Neoplasm (biosynthesis)
  • Thymidine (metabolism)
  • Tritium
  • Uridine (metabolism)

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