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The M protein of influenza viruses has no immunizing effect.

Abstract
Influenza A virus M protein was prepared by electrophoresis in SDS polyacrylamide gel from virus particles which had been pretreated with octylglucoside to remove the surface glycoproteins; M antigens from the influenza virus strains A/Victoria/3/75 (H3N2), A/FPV/Rostock (Hav1N1) and A/chick/Germany/49 (Hav2Neq1) did not protect mice against a lethal challenge infection with the virulent Victoria strain.
AuthorsH Becht, H Gruschkau, R Rott
JournalMedical microbiology and immunology (Med Microbiol Immunol) Vol. 167 Issue 4 Pg. 285-8 ( 1979) ISSN: 0300-8584 [Print] Germany
PMID545115 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Antibodies, Viral
  • Antigens, Viral
  • Viral Proteins
Topics
  • Animals
  • Antibodies, Viral (biosynthesis)
  • Antigens, Viral (immunology)
  • Hemagglutination Inhibition Tests
  • Immunization
  • Influenza A virus (immunology)
  • Mice
  • Orthomyxoviridae Infections (immunology, prevention & control)
  • Viral Proteins (immunology)

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