Abstract | UNLABELLED: RESULTS: * 73.9 percent excellent-to-good response to the active drug in patients receiving it before they received the placebo, compared with 44.5 percent in those who did not receive it until after the placebo period.* 58.9 percent excellent-to-good response to the active drug in patients who received it after the placebo period, as compared with 31.8 percent in those receiving the placebo last.* Overall clinical response 67.5 percent excellent-to-good with the active drug as compared with 37.5 percent with the placebo.* Excellent-to-good results in 12 follow-up patients receiving the known active drug.* Statistically significant symptomatic response in four of eight target symptoms. The tranquilizer- anticholinergic preparation used appeared to improve not only patient outlook and attitudes but to effectively relieve both the physiologic and psychic manifestations of common functional gastrointestinal disorders.
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Authors | H H Wayne |
Journal | California medicine
(Calif Med)
Vol. 111
Issue 2
Pg. 79-83
(Aug 1969)
ISSN: 0008-1264 [Print] United States |
PMID | 5394587
(Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, Journal Article)
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Chemical References |
- Benzilates
- Parasympatholytics
- Placebos
- Quaternary Ammonium Compounds
- Quinuclidines
- Chlordiazepoxide
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Topics |
- Adult
- Aged
- Benzilates
(therapeutic use)
- Chlordiazepoxide
(therapeutic use)
- Female
- Gastrointestinal Diseases
(drug therapy)
- Humans
- Male
- Middle Aged
- Parasympatholytics
(therapeutic use)
- Placebos
- Quaternary Ammonium Compounds
(therapeutic use)
- Quinuclidines
(therapeutic use)
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