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Experimental and clinical studies with a new antimonial preparation for the treatment of schistosomiasis.

Abstract
This paper presents the results of a clinical study in which a new antimony preparation-a chelate of dimethylcysteine with antimony sodium tartrate ("NAP")-was administered intramuscularly at a total dosage of 2 g (5x400 mg, corresponding to 290 mg of Sb) to 400 patients with schistosomiasis. Among 108 patients in a rural population the treatment was on the whole well accepted (97% completed the intensive course of injections), thus indicating that NAP would be useful for the mass treatment of schistosomiasis.
AuthorsM R Pedrique, N Ercoli
JournalBulletin of the World Health Organization (Bull World Health Organ) Vol. 45 Issue 4 Pg. 411-7 ( 1971) ISSN: 0042-9686 [Print] Switzerland
PMID5317079 (Publication Type: Journal Article)
Chemical References
  • Anthelmintics
  • Tartrates
  • Antimony
  • Sodium
  • Potassium
Topics
  • Adult
  • Anthelmintics (administration & dosage, therapeutic use)
  • Antimony (administration & dosage, therapeutic use)
  • Female
  • Humans
  • Infant, Newborn
  • Male
  • Potassium
  • Schistosomiasis (drug therapy)
  • Sodium
  • Tartrates

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