HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Blocking effect of McN-A-343 on cardiac slowing produced by vagal stimulation.

Abstract
The effect of McN-A-343 was studied by direct administration into the sinus node artery of dogs vagotomized at the mid-cervical level. McN-A-343 blocked sinus bradycardia caused by electrical stimulation of the right vagus, while bradycardia induced by administration of acetylcholine or nicotine into the sinus node artery was not modified.
AuthorsS Chiba, K Hashimoto, K Kubota, S Sato
JournalBritish journal of pharmacology (Br J Pharmacol) Vol. 43 Issue 3 Pg. 675-6 (Nov 1971) ISSN: 0007-1188 [Print] England
PMID5157729 (Publication Type: Journal Article)
Chemical References
  • Carbamates
  • Quaternary Ammonium Compounds
  • Nicotine
  • Acetylcholine
Topics
  • Acetylcholine (pharmacology)
  • Animals
  • Carbamates (pharmacology)
  • Dogs
  • Electric Stimulation
  • Heart Rate (drug effects)
  • Nicotine (pharmacology)
  • Quaternary Ammonium Compounds (pharmacology)
  • Sinoatrial Node (drug effects)
  • Vagotomy
  • Vagus Nerve (drug effects)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: