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Cell culture studies in progeria. I. Establishment and partial characterization of a lymphoblastoid cell line.

Abstract
A lymphoblastoid cell line (EKS-L44) with definitive HLA specificities (HLA-Aw24, w30, B14, w35, Cw4-, DRw4, 5) was established from peripheral blood cells of a patient with progeria using Epstein-Barr virus. Cytogenetic study indicated that EKS-L44 was diploid after four months in vitro. The growth pattern of this cell line was not significantly different from a similarly established normal control nor from other lines initiated from patients with various disorders.
AuthorsA Milunsky, Y K Tsung
JournalMechanisms of ageing and development (Mech Ageing Dev) Vol. 11 Issue 3 Pg. 185-90 (Oct 1979) ISSN: 0047-6374 [Print] Ireland
PMID513854 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • HLA Antigens
Topics
  • Cell Line
  • Child
  • Diploidy
  • HLA Antigens (genetics)
  • Humans
  • Lymphocytes (cytology)
  • Male
  • Progeria (pathology)

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