Activity and effective serum level of repository sulphones (DADDS) in lepromatous leprosy.

Abstract	35 cases of lepromatous leprosy were studied to evaluate the effective blood level and long depot action of acedapsone (DADDS). It was revealed that serum level of this drug is maintained well above the minimum inhibitory concentration upto 60 days following single intramuscular injection. No significant untoward effects of the drug were encountered except one case of Erythema Nodosum Leprosum and six patients with mild reactional symptoms in the form of fever and arthralgia.
Authors	L C Anand, B S Rathore
Journal	Leprosy in India (Lepr India) Vol. 51 Issue 3 Pg. 358-62 (Jul 1979) ISSN: 0024-1024 [Print] India
PMID	513651 (Publication Type: Journal Article)
Chemical References	Delayed-Action Preparations Acedapsone Dapsone
Topics	Acedapsone (adverse effects, blood, therapeutic use) Adult Dapsone (analogs & derivatives) Delayed-Action Preparations Female Humans Injections, Intramuscular Leprosy (drug therapy) Male Middle Aged

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