Urinary pregnanetriol and delta 5-pregnentriol in women with idiopathic hirsutism.

Abstract

Urinary pregnanetriol and delta 5-pregnenetriol were determined in 90 normal women and in 90 women with idiopathic hirsutism of comparable age group. When group Student's "t"-test was carried out, the mean steroid excretion values in hirsute women were found to be significant with delta 5-pregnenetriol more significant than pregnanetriol. Of the 90 women with hirsutism, 8 patients had pregnanetriol and delta 5-pregnenetriol values higher than normal. When, on the basis of these elevated values, the women were sent for a thorough gynaecological investigation, they were found to have the polycystic ovary syndrome. After wedge resection, the diagnosis was confirmed and the urinary excretion of pregnanetriol and delta 5-pregnenetriol came down to a normal level. This study shows that, in the case of women with idiopathic hirsutism suspected of any ovarian disorder, the measurement of these two steroids could be of diagnostic importance.

• Authors: S B Pal
• Journal: Endokrinologie (Endokrinologie) Vol. 74 Issue 1 Pg. 42-6 (Apr 1979) ISSN: 0013-7251 [Print] Germany
• PMID: 510222 (Publication Type: Journal Article)

Chemical References

• Pregnenes
• Pregnanetriol
• 5-pregnene-3 beta,17 alpha,20 alpha-triol

Topics

• Adolescent
• Adult
• Age Factors
• Female
• Hirsutism (urine)
• Humans
• Middle Aged
• Pregnanetriol (urine)
• Pregnenes (urine)
• Reference Values