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Efficacy of avermectin B1a against microfilariae of Dirofilaria immitis.

Abstract
Avermectin B1a given at a dose level of 0.05 or 0.1 mg/kg of body weight caused rapid removal of Dirofilaria immitis microfilariae from the blood of dogs with heartworm infections. If the adult worms were also killed with an arsenical (melarsoprol), the removal of microfilariae was permanent.
AuthorsL S Blair, W C Campbell
JournalAmerican journal of veterinary research (Am J Vet Res) Vol. 40 Issue 7 Pg. 1031-2 (Jul 1979) ISSN: 0002-9645 [Print] United States
PMID507489 (Publication Type: Journal Article)
Chemical References
  • Anthelmintics
  • Disaccharides
  • Lactones
  • Ivermectin
  • avermectin
Topics
  • Animals
  • Anthelmintics (therapeutic use)
  • Blood (parasitology)
  • Dirofilariasis (drug therapy, parasitology, veterinary)
  • Disaccharides (therapeutic use)
  • Dog Diseases (drug therapy, parasitology)
  • Dogs
  • Ivermectin (analogs & derivatives)
  • Lactones (therapeutic use)
  • Microfilariae

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