Abstract |
A retrosepctive evaluation has been made of blood pressure, pulse rate, and number of anginal attacks per day in twenty-one patients diagnosed as Prinzmetal's Angina and treated with the investigational drug nifedipine. The effect of combining nifedipine with short- and long-acting nitrates or with propranolol was also evaluated. In consideration of the statisically significant reduction in the number of anginal attacks per day, p less than 0.001, together with the non-significant mean changes in blood pressure and pulse rate as well as the compatibility with the other drugs, it is concluded that nifedipine is a very useful drug, in a dose range of 30--120 mg per day, for the treatment of Prinzmetal's Angina. Recorded side-effects were of minimal severity and in no case caused nifedipine therapy to be discontinued.
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Authors | R Battye, C M Ordille |
Journal | The Journal of international medical research
(J Int Med Res)
Vol. 7
Issue 5
Pg. 360-9
( 1979)
ISSN: 0300-0605 [Print] England |
PMID | 499644
(Publication Type: Journal Article)
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Chemical References |
- Pyridines
- Vasodilator Agents
- Nifedipine
|
Topics |
- Adult
- Angina Pectoris
(drug therapy)
- Angina Pectoris, Variant
(drug therapy)
- Blood Pressure
(drug effects)
- Drug Evaluation
- Female
- Humans
- Male
- Middle Aged
- Nifedipine
(therapeutic use)
- Pulse
(drug effects)
- Pyridines
(therapeutic use)
- Retrospective Studies
- Vasodilator Agents
(therapeutic use)
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