HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Postmastectomy lymphangiosarcoma: experience with three patients and electron microscopic observations in one.

Abstract
The clinical features are presented of three patients in whom lymphangiosarcoma developed after radical mastectomy followed by local irradiation. The median time between radical mastectomy and the diagnosis by biopsy of lymphangiosarcoma was 9.9 years. No form of therapy, including high-dose combination chemotherapy, appeared able to control the disease. All three patients died with residual lymphangiosarcoma and in two it was the direct cause of death. These results stress that prevention of postmastectomy lymphangiosarcoma is vital. This can be accomplished by avoiding radical mastectomy followed by local irradiation. Ultrastructural observations in one case suggest that the tumour has a primitive vasoformative origin.
AuthorsH Unruh, D I Robertson, E Karasewich
JournalCanadian journal of surgery. Journal canadien de chirurgie (Can J Surg) Vol. 22 Issue 6 Pg. 586-90 (Nov 1979) ISSN: 0008-428X [Print] Canada
PMID497934 (Publication Type: Case Reports, Journal Article)
Topics
  • Adult
  • Breast Neoplasms (radiotherapy, surgery)
  • Female
  • Humans
  • Lymphangiosarcoma (etiology, pathology)
  • Mastectomy (methods)
  • Microscopy, Electron
  • Middle Aged
  • Postoperative Complications
  • Skin Neoplasms (etiology, pathology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: