[Antineoplastic effects of violamycins depending on the number of sugar-components in the molecule (author's transl)].

Abstract

Violamycin B, an antibiotic-complex, inhibited the growth of Sarcoma 180 in a well defined manner. The products Violamycin A, BII, and BI obtained by gelfiltration, were tested against the lymphoid Leukemia L1210. The results showed an increase of the toxicity and, simultaneously, a decrease of the antineoplastic effect, depending on the number of the sugar-components.

• Authors: W Jungstand, W Gutsche, K Wohlrabe, W Koch, D G Strauss
• Journal: Archiv fur Geschwulstforschung (Arch Geschwulstforsch) Vol. 49 Issue 3 Pg. 198-200 ( 1979) ISSN: 0003-911X [Print] Germany
• Vernacular Title: Zur antineoplastischen Wirkung der Violamycine in Abhängigkeit von den im Molekül enthaltenen Zuckern.
• PMID: 496560 (Publication Type: English Abstract, Journal Article)

Chemical References

• Anti-Bacterial Agents
• Carbohydrates

Topics

• Animals
• Anti-Bacterial Agents (analysis, therapeutic use, toxicity)
• Carbohydrates (analysis)
• Female
• Leukemia L1210 (drug therapy)
• Male
• Mice
• Sarcoma 180 (drug therapy)