Loss of colicinogeny in Escherichia coli strains infected by certain resistance factors.

Abstract

The original observation that in wild-type colicinogenic Escherichia coli strains the introduction of some R factors abolish their colicin production was studied in certain col(+) strains bearing well-defined col factors. Two resistance (R) factors were used and introduced by conjugation in these strains, namely the 222 factor of Watanabe and a Salmonella typhimurium ST factor (coding for resistance to streptomycin and tetracycline only). The introduction of above mentioned R factors abolished the colicin production of col(+) strains most probably by elimination of col factors. All col factors, however, were not equally susceptible to elimination by the R factors tested, since colicin production in ML strains was abolished by infection by the 222 factor but not by the R factor of S. typhimurium ST, which is able to eliminate other col factors.

• Authors: V Krcméry, C Hurwitz, P Fredericq
• Journal: Journal of bacteriology (J Bacteriol) Vol. 102 Issue 2 Pg. 521-3 (May 1970) ISSN: 0021-9193 [Print] United States
• PMID: 4911542 (Publication Type: Journal Article)

Chemical References

• Colicins
• Sulfonamides
• Nalidixic Acid
• Chloramphenicol
• Tetracycline
• Streptomycin

Topics

• Chloramphenicol (pharmacology)
• Colicins (biosynthesis)
• Coliphages
• Conjugation, Genetic
• Crosses, Genetic
• Drug Resistance, Microbial
• Escherichia coli (drug effects, metabolism)
• Mutation
• Nalidixic Acid (pharmacology)
• Streptomycin (pharmacology)
• Sulfonamides (pharmacology)
• Tetracycline (pharmacology)