| Abstract | Five patients with primary idiopathic polymyositis developed proteinuria associated with urine sediment abnormalities. Renal biopsies disclosed a focal mesangial proliferative glomerulonephritis with deposits of immunoglobulin and complement. After treatment of the polymyositis with corticosteroids, proteinuria and urine sediment changes disappeared within 4 to 8 wk along with an improvement in the muscle disease. Although the pathogenesis remains to be determined, immune complexes may be implicated in the etiology of this renal lesion. |
| Authors | R F Dyck, A Katz, D A Gordon, M Johnson, Z Shainhouse, C J Cardella, R A Bear |
| Journal | The Journal of rheumatology
(J Rheumatol)
1979 May-Jun
Vol. 6
Issue 3
Pg. 336-44
ISSN: 0315-162X CANADA |
| PMID | 490528
(Publication Type: Journal Article)
|
| Chemical References |
- Adrenal Cortex Hormones
- Antigen-Antibody Complex
|
| Topics |
- Adrenal Cortex Hormones
(therapeutic use)
- Adult
- Antigen-Antibody Complex
- Biopsy
- Female
- Glomerulonephritis
(etiology, immunology, pathology)
- Humans
- Kidney
(pathology)
- Male
- Myositis
(complications, drug therapy)
- Proteinuria
(etiology)
|
