HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Linoleic acid hydroperoxide: impaired bacterial uptake by alveolar macrophages, a mechanism of oxidant lung injury.

Abstract
Exogenous linoleic acid hydroperoxide causes in vitro impairment of both bacterial uptake and the phagocytic stimulation of (14)CO(2) production from [1-(14)C]glucose in rabbit alveolar macrophages by an undefined effect on the cell membrane. This effect may be one mechanism for the defective pulmonary bacterial clearance characteristic of oxidant lung injury.
AuthorsA Khandwala, J B Gee
JournalScience (New York, N.Y.) (Science) Vol. 182 Issue 4119 Pg. 1364-5 (Dec 28 1973) ISSN: 0036-8075 [Print] United States
PMID4760314 (Publication Type: Journal Article)
Chemical References
  • Carbon Radioisotopes
  • Linoleic Acids
  • Peroxides
  • Carbon Dioxide
  • Phosphogluconate Dehydrogenase
  • Glucosephosphate Dehydrogenase
  • Glyceraldehyde-3-Phosphate Dehydrogenases
  • Glucose
Topics
  • Animals
  • Carbon Dioxide (biosynthesis)
  • Carbon Radioisotopes
  • Depression, Chemical
  • Glucose (metabolism)
  • Glucosephosphate Dehydrogenase (antagonists & inhibitors)
  • Glyceraldehyde-3-Phosphate Dehydrogenases (antagonists & inhibitors)
  • In Vitro Techniques
  • Linoleic Acids (pharmacology)
  • Macrophages (drug effects, enzymology, metabolism)
  • Peroxides (pharmacology)
  • Phagocytosis (drug effects)
  • Phosphogluconate Dehydrogenase (antagonists & inhibitors)
  • Rabbits
  • Staphylococcus

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: