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Cholestasis as an in vivo model for analysis of the induction of liver microsomal monooxygenases by sodium phenobarbital and 3-methylcholanthrene.

AuthorsI B Tsyrlov, N E Polyakova, O A Gromova, N B Rivkind, V V Lyakhovich
JournalBiochemical pharmacology (Biochem Pharmacol) Vol. 28 Issue 9 Pg. 1473-8 (May 01 1979) ISSN: 0006-2952 [Print] England
PMID475855 (Publication Type: Journal Article)
Chemical References
  • Peroxides
  • Deoxycholic Acid
  • Methylcholanthrene
  • Mixed Function Oxygenases
  • Oxidoreductases
  • Phenobarbital
Topics
  • Animals
  • Cholestasis (enzymology)
  • Deoxycholic Acid (pharmacology)
  • Enzyme Induction (drug effects)
  • In Vitro Techniques
  • Kinetics
  • Lipid Metabolism
  • Male
  • Methylcholanthrene (pharmacology)
  • Microsomes, Liver (enzymology)
  • Mixed Function Oxygenases (biosynthesis)
  • Models, Biological
  • Oxidoreductases (biosynthesis)
  • Oxygen Consumption (drug effects)
  • Peroxides (metabolism)
  • Phenobarbital (pharmacology)
  • Rats

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