Efficacy of oxfendazole against inhibited Ostertagia ostertagi in naturally infected cattle.

Abstract

Oxfendazole was administered to pregnant cows at 2.5 and 5 mg/kg body weight to determine the anthelmintic efficacy against naturally acquired larvae which became inhibited at the early 4th stage. The experimental design included three groups of orally-treated cows, that is, 10 placebo treated control cows, 11 cows treated with 2.5 mg/kg of oxfendazole and 10 cows treated with 5.0 mg/kg of oxfendazole. Oxfendazole at 2.5 mg/kg body weight was 82 and 94% effective against EL-4 and adult O. ostertagi, respectively. At 5 mg/kg, Oxfendazole was 95 and 99% effective against EL-4 And adult O. ostertagi, respectively. The results suggested the use of a field dosage level of 5 mg/kg body weight oxfendazole where inhibited larvae may be encountered.

• Authors: T P Kistner, D Wyse, E Averkin
• Journal: Australian veterinary journal (Aust Vet J) Vol. 55 Issue 5 Pg. 232-5 (May 1979) ISSN: 0005-0423 [Print] England
• PMID: 475680 (Publication Type: Journal Article)

Chemical References

• Antinematodal Agents
• Benzimidazoles
• Carbamates

Topics

• Animals
• Antinematodal Agents (therapeutic use)
• Benzimidazoles (therapeutic use)
• Carbamates (therapeutic use)
• Cattle
• Cattle Diseases (drug therapy, parasitology)
• Female
• Larva
• Ostertagiasis (drug therapy, parasitology, veterinary)
• Pregnancy
• Trichostrongyloidea (drug effects)
• Trichostrongyloidiasis (veterinary)