Treatment of chorea gravidarum with haloperidol.

Abstract

Treatment of a case of severe chorea gravidarum with haloperidol is presented. A possible neuropharmacologic explanation of the beneficial effects of the neuroleptics, particularly haloperidol, is offered based on the dopamine antagonism of these drugs. Heightened dopaminergic activity in the striatum is postulated as the basis for the chorea. Indications for the use of haloperidol in chorea gravidarum are discussed.

• Authors: J F Patterson
• Journal: Southern medical journal (South Med J) Vol. 72 Issue 9 Pg. 1220-1 (Sep 1979) ISSN: 0038-4348 [Print] United States
• PMID: 472859 (Publication Type: Case Reports, Journal Article)

Chemical References

• Receptors, Dopamine
• Haloperidol

Topics

• Adolescent
• Chorea (drug therapy)
• Dose-Response Relationship, Drug
• Female
• Haloperidol (administration & dosage, therapeutic use)
• Humans
• Pregnancy
• Pregnancy Complications (drug therapy)
• Receptors, Dopamine (drug effects)