[Lineal clinico-pharmacological study of butibufen in rheumatic diseases].

Abstract

The analgesic and antiinflammatory effects of a new synthetic drug, a derivative of p-alcalonic (Butibufen) was studied in 21 patients with osteoarthritis localced mainly in the hip joint and knees. The parameters used in the study, clinical analytical and radiological were paralleled with a statistical study according to the Student test and show a favorable therapeutic response to the drug with an ample statistical significance. The tolerance levels investigated based on the supposed side effectos of Butibufen show that the incidence of such is very low.

• Authors: R Martí-Massó, J Honorato, G Martínez
• Journal: Revista de medicina de la Universidad de Navarra (Rev Med Univ Navarra) 1974 Sep-Dec Vol. 18 Issue 3-4 Pg. 165-78 ISSN: 0556-6177 [Print] Spain
• Vernacular Title: Estudio clínico-farmacológico lineal del butibufen en afecciones reumáticas
• PMID: 4620372 (Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, English Abstract, Journal Article)

Chemical References

• Anti-Inflammatory Agents
• Phenylbutyrates

Topics

• Adult
• Aged
• Anti-Inflammatory Agents (therapeutic use)
• Arthritis, Rheumatoid (drug therapy)
• Clinical Trials as Topic
• Drug Evaluation
• Female
• Humans
• Male
• Middle Aged
• Phenylbutyrates (therapeutic use)