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Difenoxine (R 15403), the active metabolite of diphenoxylate (R 1132). 5. Clinical comparison of difenoxine and diphenoxylate in volunteers and in patients with chronic diarrhea. Double-blind cross-over assessments.

AuthorsR Rubens, H Verhaegen, J Brugmans, V Schuermans
JournalArzneimittel-Forschung (Arzneimittelforschung) Vol. 22 Issue 3 Pg. 526-9 (Mar 1972) ISSN: 0004-4172 [Print] Germany
PMID4556767 (Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, Journal Article, Randomized Controlled Trial)
Chemical References
  • Cyanides
  • Gastrointestinal Agents
  • Isonipecotic Acids
  • Placebos
Topics
  • Adult
  • Aged
  • Clinical Trials as Topic
  • Constipation (chemically induced)
  • Cyanides (administration & dosage, adverse effects, therapeutic use)
  • Diarrhea (drug therapy)
  • Female
  • Gastrointestinal Agents (administration & dosage, adverse effects, therapeutic use)
  • Humans
  • Isonipecotic Acids (administration & dosage, adverse effects, therapeutic use)
  • Male
  • Middle Aged
  • Placebos

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