Abstract |
A critical test was performed to evaluate the anthelmintic properties of an injectable butamisole formulation and to compare the efficiency with that of a commercially available piperazine- thiabendazole anthelmintic. The test was done in 10 horses and 15 ponies with naturally acquired parasitic infections. Butamisole was administered at the dose level of 2.5 or 3.75 mg/kg of body weight by either subcutaneous or deep intramuscular injection. Given at the dose level of 2.5 mg/kg, butamisole was highly effective (99%) against Strongylus vulgaris and moderately effective (49%) against Parascaris equorum. At the 3.75 mg/kg dose rate, butamisole was highly effective against both S vulgaris (97%) and P equorum (94%). Butamisole had limited efficacy against other parasite species. Signs of toxicosis, long-term swelling of the injection sites, or tissue damage were not seen after injection.
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Authors | R B Grieve, B G Moore, R E Bradley Sr |
Journal | American journal of veterinary research
(Am J Vet Res)
Vol. 40
Issue 1
Pg. 139-41
(Jan 1979)
ISSN: 0002-9645 [Print] United States |
PMID | 453676
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
- Anthelmintics
- Imidazoles
- Piperazines
- Thiazoles
- Thiabendazole
- butamisole
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Topics |
- Animals
- Anthelmintics
(therapeutic use)
- Horse Diseases
(drug therapy)
- Horses
- Imidazoles
(administration & dosage, therapeutic use)
- Injections, Intramuscular
- Injections, Subcutaneous
- Nematode Infections
(drug therapy, veterinary)
- Piperazines
(therapeutic use)
- Strongyle Infections, Equine
(drug therapy)
- Thiabendazole
(therapeutic use)
- Thiazoles
(administration & dosage, therapeutic use)
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