Abstract |
The experience from the University of Minnesota with routine reoperations in cancers classified as Dukes' C suggests only a small minority of patients found to have asymptomatic recurrences will benefit from an additional operation. Also, morbidity and mortality will be significant. The presence of a rising carcinoembryonic antigen level following a potentially curative operation has been suggested as a more selective indicator for reoperation. Unfortunately, carcinoembryonic antigen levels are a far more sensitive indicator of hepatic metastases, the group usually not helped by operation. Patients with local-regional recurrent carcinoma of the colon and rectum--the group most likely to benefit from reoperation--often have normal carcinoembryonic antigen levels. The importance of patient selectivity for reoperation and the usefulness of the Astler-Coller staging system to define risk factors are stressed.
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Authors | A M Cohen, W C Wood |
Journal | Surgery, gynecology & obstetrics
(Surg Gynecol Obstet)
Vol. 149
Issue 1
Pg. 22-6
(Jul 1979)
ISSN: 0039-6087 [Print] United States |
PMID | 451823
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Carcinoembryonic Antigen
(analysis)
- Colonic Neoplasms
(immunology, surgery)
- Humans
- Liver Neoplasms
- Neoplasm Metastasis
- Neoplasm Recurrence, Local
- Rectal Neoplasms
(immunology, surgery)
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