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The reversal of experimental porphyria and the prevention of induction of hepatic mixed-function oxidase by acetate.

AuthorsW N Piper, T R Tephly
JournalArchives of biochemistry and biophysics (Arch Biochem Biophys) Vol. 164 Issue 1 Pg. 351-6 (Sep 1974) ISSN: 0003-9861 [Print] United States
PMID4372951 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Acetates
  • Cytochrome c Group
  • Dicarboxylic Acids
  • Porphyrins
  • Pyridines
  • Sulfanilamides
  • Porphobilinogen
  • Aminolevulinic Acid
  • Cytochrome P-450 Enzyme System
  • Mixed Function Oxygenases
  • Oxidoreductases
  • Cytochrome Reductases
  • 5-Aminolevulinate Synthetase
  • Phenobarbital
Topics
  • 5-Aminolevulinate Synthetase (biosynthesis)
  • Acetates (pharmacology, therapeutic use)
  • Aminolevulinic Acid (urine)
  • Animals
  • Cytochrome P-450 Enzyme System (metabolism)
  • Cytochrome Reductases (biosynthesis)
  • Cytochrome c Group
  • Dicarboxylic Acids
  • Enzyme Induction (drug effects)
  • Liver (drug effects, enzymology)
  • Male
  • Microsomes, Liver (drug effects, enzymology)
  • Mixed Function Oxygenases (biosynthesis)
  • Oxidoreductases (biosynthesis)
  • Phenobarbital (pharmacology)
  • Porphobilinogen (urine)
  • Porphyrias (chemically induced, drug therapy, enzymology, urine)
  • Porphyrins (urine)
  • Pyridines
  • Rats
  • Spectrophotometry
  • Sulfanilamides (pharmacology)

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