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Activation by reductive cleavage of potentially cytotoxic azo compounds by human hepatocellular carcinoma.

AuthorsH Autrup, B J Thurlow, G P Warwick
JournalBiochemical pharmacology (Biochem Pharmacol) Vol. 23 Issue 16 Pg. 2341-5 (Aug 15 1974) ISSN: 0006-2952 [Print] UNITED STATES
PMID4368368 (Publication Type: Journal Article)
Chemical References
  • Antineoplastic Agents
  • Azo Compounds
  • Neoplasm Proteins
Topics
  • Animals
  • Antineoplastic Agents (metabolism)
  • Azo Compounds (metabolism)
  • Carcinoma, Hepatocellular (chemically induced, enzymology, metabolism)
  • Female
  • Haplorhini
  • Humans
  • Kinetics
  • Liver (enzymology)
  • Liver Neoplasms (chemically induced, enzymology, metabolism)
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Neoplasm Proteins (analysis)
  • Oxidation-Reduction
  • Papio
  • Rats
  • Structure-Activity Relationship

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