Chronic mucocutaneous candidiasis. Successful treatment with intermittent oral doses of clotrimazole.

Abstract

Treatment of chronic mucocutaneous candidiasis has included drugs, immunotherapy, and replacement of nutritional and endocrine deficiency. Although amphotericin B is the best known and most commonly used form of treatment, the imidazole antibiotic clotrimazole has shown promise as an effective agent that can be given orally with low toxicity. A 9-year-old girl responded to intermittent clotrimazole therapy with complete and prolonged remission. This form of treatment offers advantages in safety and effectiveness over other therapies for chronic mucocutaneous candidiasis.

• Authors: A S Rockoff
• Journal: Archives of dermatology (Arch Dermatol) Vol. 115 Issue 3 Pg. 322-3 (Mar 1979) ISSN: 0003-987X [Print] United States
• PMID: 434848 (Publication Type: Case Reports, Journal Article)

Chemical References

• Imidazoles
• Clotrimazole

Topics

• Administration, Oral
• Candidiasis, Cutaneous (drug therapy)
• Child
• Chronic Disease
• Clotrimazole (administration & dosage, adverse effects, therapeutic use)
• Drug Administration Schedule
• Female
• Humans
• Imidazoles (administration & dosage)
• Mucous Membrane (drug effects)