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Peroxidase-mediated virucidal systems.

Abstract
Peroxidase (myeloperoxidase or lactoperoxidase), hydrogen peroxide, and a halide such as iodide, bromide, or chloride form a potent virucidal system that is effective against polio and vaccinia viruis, particularly at a low pH. The peroxidase-halide-hydrogen peroxide system may contribute to the host defense against certain viral infections.
AuthorsM E Belding, S J Klebanoff, C G Ray
JournalScience (New York, N.Y.) (Science) Vol. 167 Issue 3915 Pg. 195-6 (Jan 09 1970) ISSN: 0036-8075 [Print] United States
PMID4311694 (Publication Type: Journal Article)
Chemical References
  • Antiviral Agents
  • Bromides
  • Chlorides
  • Iodides
  • Hydrogen Peroxide
  • Peroxidases
Topics
  • Antiviral Agents (pharmacology)
  • Bromides
  • Chlorides
  • Cytopathogenic Effect, Viral
  • Hydrogen Peroxide
  • Hydrogen-Ion Concentration
  • Iodides
  • Peroxidases (pharmacology)
  • Poliovirus (drug effects)
  • Vaccinia virus (drug effects)
  • Virus Cultivation

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