| Abstract | It was shown in comparative experiments on guinea pigs that the oral method of immunization with plague vaccine was much less effective than the inhalation and subcutaneous. Guinea pigs were found to be a poor model for studying the efficacy of oral immunization with dry live plague vaccine rehydrated before use: with the use of this preparation the animals were 46 times less resistant to aerosol plague infection than in application of strain EB cultured in agar. |
| Authors | Iu V Chicherin, A A Vorob'ev, V I Evstigneev, V A Lebedinskiĭ, E M Zemskov |
| Journal | Zhurnal mikrobiologii, epidemiologii, i immunobiologii
(Zh Mikrobiol Epidemiol Immunobiol)
Issue 1
Pg. 102-4
(Jan 1979)
ISSN: 0372-9311 USSR |
| Vernacular Title | Dal'neĭshee izuchenie éffektivnosti peroral'nogo sposoba immunizatsii protiv chumy v éksperimente na zhivotnykh. |
| PMID | 425749
(Publication Type: Comparative Study, English Abstract, Journal Article)
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| Chemical References |
|
| Topics |
- Administration, Oral
- Aerosols
- Animals
- Guinea Pigs
- Injections, Subcutaneous
- Plague
(prevention & control)
- Plague Vaccine
(administration & dosage)
- Vaccination
|
