Abstract |
The title compound, which belongs to a new synthetic group of polycyclic lactones derived from isocoumarin, exhibits a remarkably high degree of carcinogenicity in situ when injected in mice. Cancer-inducing activity has also been found in similar isocoumarins, a family known to include many naturally occurring substances.
|
Authors | A Lacassagne, N P Buu-Hoi, F Zajdela, P Jacquigmon, M Mangane |
Journal | Science (New York, N.Y.)
(Science)
Vol. 158
Issue 3799
Pg. 387-8
(Oct 20 1967)
ISSN: 0036-8075 [Print] United States |
PMID | 4168747
(Publication Type: Journal Article)
|
Chemical References |
- Carcinogens
- Lactones
- Polycyclic Compounds
|
Topics |
- Animals
- Carcinogens
- Female
- Lactones
- Male
- Mice
- Polycyclic Compounds
- Sarcoma, Experimental
(chemically induced)
|