Effect of Freund's adjuvant on standard dark and pastel mink.

Abstract

Following a long series of injections of homologous immunoglobulin in complete and incomplete Freund's adjuvant into mink, a moderate elevation in the level of gammaglobulin in the serum was observed in a few animals. Relatively mild pathological changes also were seen in liver, spleen, lymph nodes, lungs and kidney. It is concluded that the injection of Freund's adjuvant, under the experimental conditions described, produced lesions which were readily distinguishable from the lesions characteristic of aleutian disease of mink.

• Authors: H Tabel, D G Ingram
• Journal: Canadian journal of comparative medicine : Revue canadienne de medecine comparee (Can J Comp Med) Vol. 35 Issue 2 Pg. 115-20 (Apr 1971) ISSN: 0008-4050 [Print] Canada
• PMID: 4103598 (Publication Type: Journal Article)

Chemical References

• Immunoglobulins
• gamma-Globulins
• Freund's Adjuvant

Topics

• Aleutian Mink Disease (diagnosis, pathology)
• Animals
• Blood Protein Disorders (diagnosis)
• Diagnosis, Differential
• Freund's Adjuvant
• Hypergammaglobulinemia
• Immunoglobulins (analysis)
• Kidney Diseases (diagnosis)
• Liver Diseases (diagnosis)
• Lymph Nodes (pathology)
• Mink
• Splenic Diseases (diagnosis)
• gamma-Globulins (analysis)