Helminthiasis, mite-allergy and IgE in a homogenous tropical population.

Abstract

Of 77 eosinophilic male adolescents studied, 12% were found to have helminthiasis and high circulating serum levels of IgE to Dermatophagoides pteronyssinus. This shows that worm-infested individuals can still mount high IgE responses to atopic non-helminthic allergens. The total serum IgE levels of these individuals were not significantly different from those with helminthiasis only, suggesting that there may be some form of repression of helminth-induced non-specific IgE in the presence of atopy; alternatively, allergen-related IgE may be repressed when an individual is worm-infested.

• Authors: C G Teo, M Singh, L C Ho
• Journal: Annals of tropical medicine and parasitology (Ann Trop Med Parasitol) Vol. 79 Issue 5 Pg. 495-9 (Oct 1985) ISSN: 0003-4983 [Print] England
• PMID: 4083958 (Publication Type: Journal Article)

Chemical References

• Immunoglobulin E

Topics

• Adolescent
• Eosinophils
• Helminthiasis (immunology)
• Humans
• Hypersensitivity, Immediate (immunology)
• Immunoglobulin E (metabolism)
• Leukocyte Count
• Male
• Mites (immunology)