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Efficacy of morantel against nematode populations in calves exposed on a pasture stocked for two years with morantel sustained-release bolus-treated calves.

Abstract
Two groups of 10 parasite-free calves were maintained either for 2 weeks on a pasture grazed by nonmedicated cattle (pasture A) or for 3 weeks on a pasture grazed by morantel sustained-release bolus-treated cattle (pasture B) for the preceding 2 years. After a 4-week holding period to allow for maturation of acquired gastrointestinal nematodes, 5 calves from each group were administered a therapeutic dose (10 mg/kg of body weight) of morantel tartrate. All calves were necropsied 1 week later, and the abomasal and small intestinal nematodes were isolated, identified, and enumerated. A comparison of efficacies between nonmedicated and morantel tartrate-treated calves of each pasture demonstrated that morantel was equally effective against the gastrointestinal nematode infections, regardless of infection source (ie, pasture A vs pasture B). The overall nematode reductions due to morantel tartrate treatment of calves that grazed pastures A and B were 98% and 96%, respectively. It was concluded that the sensitivity of gastrointestinal nematodes to morantel tartrate was not diminished in calves maintained on pasture B, which had been stocked with morantel sustained-release bolus-treated calves for the preceding 2 grazing seasons.
AuthorsT J Newby, T A Yazwinski, B L Presson, T E Greenway, H M Holtzen, M J Bischoff, H E Featherstone
JournalAmerican journal of veterinary research (Am J Vet Res) Vol. 46 Issue 12 Pg. 2437-9 (Dec 1985) ISSN: 0002-9645 [Print] United States
PMID4083575 (Publication Type: Journal Article)
Chemical References
  • Delayed-Action Preparations
  • Pyrimidines
  • Morantel
Topics
  • Animals
  • Cattle
  • Cattle Diseases (prevention & control)
  • Delayed-Action Preparations
  • Male
  • Morantel (administration & dosage)
  • Nematode Infections (prevention & control, veterinary)
  • Pyrimidines (administration & dosage)

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