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[Clinical evaluation on combination therapy of antibiotics and a gamma-globulin preparation (SM-4300) in the field of pediatrics].

Abstract
Ten cases of bacterial infections, showing no or insufficient response to antibacterial chemotherapy, were treated with a new intravenous human gamma-globulin (SM-4300). SM-4300 was administered intravenously (68-172 mg/kg/day) once a day for 1-3 days. SM-4300 was effective in 6 out of 8 pneumonia cases and also in 1 out of 2 septicemia cases. In none of the 10 cases, any side effects were observed.
AuthorsN Suzuki, A Watanabe
JournalThe Japanese journal of antibiotics (Jpn J Antibiot) Vol. 38 Issue 9 Pg. 2571-6 (Sep 1985) ISSN: 0368-2781 [Print] Japan
PMID4079022 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Anti-Bacterial Agents
  • Immunoglobulins
  • SM-4300
Topics
  • Adolescent
  • Anti-Bacterial Agents (administration & dosage)
  • Bacteria (immunology)
  • Bacterial Infections (therapy)
  • Bronchopneumonia (therapy)
  • Child
  • Child, Preschool
  • Drug Evaluation
  • Drug Resistance, Microbial
  • Drug Therapy, Combination
  • Female
  • Humans
  • Immunization, Passive
  • Immunoglobulins (administration & dosage)
  • Infant
  • Male
  • Pneumonia (therapy)

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