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Impotence responsive to glyceryl trinitrate.

Abstract
The author presents suggestive evidence that glyceryl trinitrate served to treat and diagnose atherosclerotic impotence in a man with psychogenic impotence. The prevalence of atherosclerotic impotence is not known but may be relatively high in older men. Vasodilators may be effective in diagnosing these patients, who do not have clear signs of arterial insufficiency of the lower extremities (e.g., Leriche's syndrome). The author postulates a pharmacological interaction between organic nitrates and imipramine.
AuthorsJ W Mudd
JournalThe American journal of psychiatry (Am J Psychiatry) Vol. 134 Issue 8 Pg. 922-5 (Aug 1977) ISSN: 0002-953X [Print] United States
PMID406802 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Pentaerythritol Tetranitrate
  • Nitroglycerin
  • Imipramine
Topics
  • Angina Pectoris (drug therapy)
  • Arteriosclerosis (complications)
  • Depression (drug therapy)
  • Erectile Dysfunction (drug therapy, etiology)
  • Humans
  • Imipramine (pharmacology, therapeutic use)
  • Male
  • Middle Aged
  • Nitroglycerin (pharmacology, therapeutic use)
  • Pentaerythritol Tetranitrate (pharmacology, therapeutic use)

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