Abstract |
The role of subclinical intrauterine infection in preterm labor was evaluated prospectively in 40 patients and appropriate control subjects. The 24 preterm labor patients (60%) with a negative C-reactive protein value responded to tocolysis 95.8% of the time, with a mean delay of delivery of 35.5 days and a mean gestational age of 36.9 weeks. The 16 patients (40%) with a positive C-reactive protein value responded to tocolysis only 37.5% of the time, with a mean delay of delivery of 14.4 days and a mean gestational age of 33.2 weeks. Pathologic evidence of chorioamnionitis was present in 32.9% of 310 preterm deliveries as compared to only 22.3% of 1631 term deliveries. The presence of subclinical infection must be considered in cases of preterm labor, especially among patients for whom tocolytic therapy is unsuccessful.
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Authors | R K Potkul, A H Moawad, K L Ponto |
Journal | American journal of obstetrics and gynecology
(Am J Obstet Gynecol)
Vol. 153
Issue 6
Pg. 642-5
(Nov 15 1985)
ISSN: 0002-9378 [Print] United States |
PMID | 4061533
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Adult
- C-Reactive Protein
- Chorioamnionitis
(complications, diagnosis)
- Female
- Gestational Age
- Humans
- Obstetric Labor, Premature
(etiology)
- Pregnancy
- Pregnancy Complications, Infectious
(diagnosis)
- Prospective Studies
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