HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Post-operative analgesia by epidural versus intramuscular nicomorphine after thoracotomy. Part I.

Abstract
One hundred and sixty-three patients subjected to three different types of thoracic operation were allocated randomly either to balanced intravenous anaesthesia including i.v. opiates with post-operative intramuscular opiates (intramuscular group) or to balanced intravenous anaesthesia without i.v. opiates but with high thoracic epidural regional block during the operation as well as epidural nicomorphine post-operatively (epidural group). Post-operative nicomorphine was given only at the request of the patient and as frequently as needed to obtain satisfactory pain relief. Patients in the epidural group received nicomorphine exclusively by epidural injection. In this paper (Part I), general parameters between the epidural group and the im. group are compared. The epidural group showed acceptable cardiovascular stability during the operation. With the catheter tip at the T3-T4 level, there was apparently a preferential spread downwards of the local anaesthetics. Post-operatively both groups (i.m. and epidural) provided effective and rapid onset of analgesia. There were no major differences in post-operative pain assessment, either by the patient or by the team.
AuthorsM Hasenbos, J van Egmond, M Gielen, J F Crul
JournalActa anaesthesiologica Scandinavica (Acta Anaesthesiol Scand) Vol. 29 Issue 6 Pg. 572-6 (Aug 1985) ISSN: 0001-5172 [Print] England
PMID4060998 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)
Chemical References
  • Morphine Derivatives
  • Nicotinic Acids
  • nicomorphine
Topics
  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Analysis of Variance
  • Anesthesia
  • Body Weight
  • Catheterization (methods)
  • Epidural Space
  • Female
  • Humans
  • Injections, Intramuscular
  • Male
  • Middle Aged
  • Morphine Derivatives (administration & dosage)
  • Nicotinic Acids (administration & dosage)
  • Pain, Postoperative (drug therapy)
  • Posture
  • Sex Factors
  • Thoracic Surgery

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: