Sodium cromoglycate in ragweed-allergic conjunctivitis.

Abstract

Sodium cromoglycate (SCG), in a 4% solution instilled into each eye 4 times daily, was compared with placebo in a double-blind, noncrossover trial in 30 matched patients with troublesome ragweed pollen-induced conjunctivitis. In the SCG group, eye symptom scores were significantly less (p = 0.05), and all patients judged that their symptoms were improved over the previous year (p less than 0.05). Less antihistamine was used by the SCG group but the difference was not significant. It was concluded that SCG was effective in the treatment of ragweed-induced seasonal allergic conjunctivitis.

• Authors: J Greenbaum, D Cockcroft, F E Hargreave, J Dolovich
• Journal: The Journal of allergy and clinical immunology (J Allergy Clin Immunol) Vol. 59 Issue 6 Pg. 437-9 (Jun 1977) ISSN: 0091-6749 [Print] United States
• PMID: 405408 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)

Chemical References

• Cromolyn Sodium

Topics

• Clinical Trials as Topic
• Conjunctivitis (drug therapy, etiology)
• Cromolyn Sodium (administration & dosage, therapeutic use)
• Humans
• Pollen
• Rhinitis, Allergic, Seasonal (complications)