HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Intraarterial analgesia in peripheral arteriography.

Abstract
A pilot study involving 36 patients was undertaken to test the efficacy of combining 1% lidocaine with 60% methylglucamine iothalamate for relief of the severe burning pain often experienced during peripheral arteriography. Of 24 patients premedicated with meperidine hydrochloride and promethazine hydrochloride, 12 received lidocaine with the contrast medium and 12 did not. The remaining 12 patients were premedicated with diazepam and received lidocaine with the contrast material. By both subjective and objective criteria, those patients receiving lidocaine in the intraarterial injection of contrast medium suffered less pain. Optimum results were achieved for the lidocaine group receiving analgesic premedication. No adverse reactions attributable to the lidocaine were encountered. Subsequent to completion of the pilot study, more than 300 patients have been studied with similar impressive results of pain relief and safety.
AuthorsD F Guthaner, J F Silverman, W G Hayden, L Wexler
JournalAJR. American journal of roentgenology (AJR Am J Roentgenol) Vol. 128 Issue 5 Pg. 737-9 (May 1977) ISSN: 0361-803X [Print] United States
PMID404894 (Publication Type: Journal Article)
Chemical References
  • Lidocaine
  • Meperidine
  • Promethazine
  • Diazepam
Topics
  • Analgesia
  • Angiography
  • Diazepam
  • Humans
  • Injections, Intra-Arterial
  • Lidocaine (administration & dosage)
  • Meperidine
  • Premedication
  • Promethazine

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: