[A fatal case of farmer's lung: a study of specific classes of antibodies in the serum and broncho-alveolar lavage].

Abstract

A 61 year old agricultural worker, without any respiratory past history, presented with a pulmonary fibrosis of rapid and fatal outcome. This was due to an extrinsic allergic fibrosing alveolitis of the Farmer's lung type. A search for precipitins "vis-à-vis" Micropolyspora faeni was strongly positive in the serum and broncho-alveolar lavage. Specific IgA antibodies to M. faeni, as well as specific antigenic fractions of M. faeni were demonstrated in the broncho-alveolar lavage. This IgA was almost certainly produced locally.

• Authors: M Gari, P Richebe, B Mouysset, J M Pinon
• Journal: Revue des maladies respiratoires (Rev Mal Respir) Vol. 2 Issue 1 Pg. 11-4 ( 1985) ISSN: 0761-8425 [Print] France
• Vernacular Title: Un cas mortel de maladie de poumon du fermier: étude des classes d'anticorps spécifiques dans le sérum et le lavage broncho-alvéolaire.
• PMID: 4012009 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Antibodies, Bacterial
• Immunoglobulin A
• Immunoglobulin Fragments

Topics

• Antibodies, Bacterial (analysis, classification)
• Bronchi (immunology)
• Enzyme-Linked Immunosorbent Assay
• Exudates and Transudates (immunology)
• Farmer's Lung (immunology, microbiology)
• Humans
• Immunoglobulin A (analysis)
• Immunoglobulin Fragments (analysis)
• Male
• Micromonosporaceae (immunology)
• Middle Aged
• Therapeutic Irrigation