| Abstract | Three cases of contact allergy to Kathon CG, a preservative for cosmetics and toiletries containing, as active ingredients, 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one are presented. In two patients, Kathon CG was contained in a moisturizing cream, and the third was sensitized by a diagnostic patch test. Although it has been used extensively in cosmetics and toiletries for 9 years in Europe and 4 years in the USA, these appear to be the first case reports of non-occupational sensitization to Kathon CG. |
| Authors | A C de Groot, D H Liem, J W Weyland |
| Journal | Contact dermatitis
(Contact Dermatitis)
Vol. 12
Issue 2
Pg. 76-80
(Feb 1985)
ISSN: 0105-1873 DENMARK |
| PMID | 3987260
(Publication Type: Case Reports, Journal Article)
|
| Chemical References |
- Cosmetics
- Mutagens
- Pharmaceutic Aids
- Preservatives, Pharmaceutical
- Thiazoles
- Kathon 886
|
| Topics |
- Adult
- Chemistry
- Cosmetics
(adverse effects)
- Dermatitis, Contact
(etiology)
- Female
- Humans
- Middle Aged
- Mutagens
(adverse effects)
- Patch Tests
- Pharmaceutic Aids
(adverse effects)
- Preservatives, Pharmaceutical
(adverse effects)
- Thiazoles
(adverse effects)
|
