| Abstract | Ten male patients with advanced cancer of the breast were treated with cyproterone acetate, an anti-androgenic compound with additional progestational properties. Seven patients achieved a response, for a median duration of 8 months. Plasma testosterone and estradiol levels fell significantly during therapy, but quantitatively this drop was not related to the therapeutic response. Cyproterone acetate is an effective and well-tolerated treatment for metastatic male breast cancer. |
| Authors | M Lopez |
| Journal | Cancer
(Cancer)
Vol. 55
Issue 10
Pg. 2334-6
(May 15 1985)
ISSN: 0008-543X UNITED STATES |
| PMID | 3986737
(Publication Type: Journal Article)
|
| Chemical References |
- Cyproterone
- Estradiol
- Testosterone
- Prolactin
|
| Topics |
- Aged
- Breast Neoplasms
(blood, drug therapy)
- Cyproterone
(adverse effects, therapeutic use)
- Drug Evaluation
- Erectile Dysfunction
(chemically induced)
- Estradiol
(blood)
- Humans
- Male
- Middle Aged
- Neoplasm Metastasis
- Prolactin
(blood)
- Testosterone
(blood)
|
