Abstract |
Forty-nine patients with plaque-type psoriasis were enrolled in a randomized prospective trial that compared the efficacy of outpatient treatment with suberythemogenic doses of ultraviolet B (UVB) radiation administered with a tar oil to treatment with maximally erythemogenic UVB radiation with emollients. Seventeen percent of patients treated with tar oil and 26% of patients treated with maximally erythemogenic UVB failed to adhere to the protocol. Although the tar oil protocol seemed slightly less effective in those with more severe psoriasis, a roughly comparable fraction of patients who adhered to either protocol cleared at least 90% of psoriasis on surfaces exposed to UVB (76% vs 100%). The total dose of UVB to clearing was 44% less for patients treated with tar oil and suberythemogenic UVB. For most patients with moderate psoriasis, suberythemogenic UVB and tar oil is an effective, low-cost, and acceptable outpatient therapy.
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Authors | A Menkes, R S Stern, K A Arndt |
Journal | Journal of the American Academy of Dermatology
(J Am Acad Dermatol)
Vol. 12
Issue 1 Pt 1
Pg. 21-5
(Jan 1985)
ISSN: 0190-9622 [Print] United States |
PMID | 3980799
(Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)
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Chemical References |
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Topics |
- Adult
- Coal Tar
(therapeutic use)
- Female
- Humans
- Male
- Photochemotherapy
- Prospective Studies
- Psoriasis
(drug therapy)
- Radiotherapy Dosage
- Random Allocation
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