[Modification of the action of ionizing radiation on cells of transplantable tumors by administering xanthobine].

Abstract

In experiments on mice it was established that the radiosensitizing effect of xanthobin was manifested by the enhancement of the inhibiting action of ionizing radiation on the growth of adenocarcinoma RL-67, diminution of the "shoulder" of the survival curve of Ehrlich ascites tumor cells, and increase in the average life of tumor-bearing animals.

• Authors: V A Volchkov, N Ia Mikhaĭlova, V B Klimovich
• Journal: Radiobiologiia (Radiobiologiia) 1985 Jan-Feb Vol. 25 Issue 1 Pg. 112-4 ISSN: 0033-8192 [Print] Russia (Federation)
• Vernacular Title: Modifikatsiia deĭstviia ioniziruiushche radiatsii na kletki perevivaemykh opukhole pri vvedenii ksantobina.
• PMID: 3975364 (Publication Type: English Abstract, Journal Article)

Chemical References

• Radiation-Sensitizing Agents
• xanthobine
• Caffeine

Topics

• Adenocarcinoma (drug therapy, radiotherapy)
• Animals
• Caffeine (analogs & derivatives, therapeutic use)
• Carcinoma, Ehrlich Tumor (drug therapy, radiotherapy)
• Combined Modality Therapy
• Mice
• Neoplasm Transplantation
• Neoplasms, Experimental (drug therapy, radiotherapy)
• Radiation-Sensitizing Agents (therapeutic use)