Sarcoid myopathy with elevated creatine phosphokinase.

Abstract

Acute inflammatory myopathy complicating sarcoidosis is rare, and its prognosis and appropriate therapy have not been defined well. We describe a patient with chronic sarcoidosis who, during a 3-month period, developed an acute proximal myopathy associated with marked elevations in creatine phosphokinase (CPK) and extensive granulomatous inflammation on muscle biopsy. High-dose corticosteroids were dramatically effective in inducing remission, with resolution of all signs and symptoms of the myopathy and normalization of CPK.

• Authors: D G Ando, J P Lynch 3rd, J C Fantone 3rd
• Journal: The American review of respiratory disease (Am Rev Respir Dis) Vol. 131 Issue 2 Pg. 298-300 (Feb 1985) ISSN: 0003-0805 [Print] United States
• PMID: 3970459 (Publication Type: Case Reports, Journal Article)

Chemical References

• Creatine Kinase
• Prednisone

Topics

• Adult
• Biopsy
• Creatine Kinase (blood)
• Humans
• Male
• Muscles (pathology)
• Muscular Diseases (drug therapy, enzymology, pathology)
• Prednisone (therapeutic use)
• Sarcoidosis (drug therapy, enzymology, pathology)