Abstract |
We present two patients with an aggressive form of sclerosing mesenteritis characterized by a progressive, life-threatening course, prominent retroperitoneal disease, and tubuloreticular structures in one case, an ultrastructural feature associated with autoimmune and cyclophosphamide-responsive diseases. In both patients, aggressive immunosuppressive medical therapy with cyclophosphamide resulted in prompt, dramatic improvement, without recurrence. When the diagnosis of sclerosing mesenteritis is established, we recommend early aggressive medical therapy with cyclophosphamide, particularly when tubuloreticular structures are present.
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Authors | R W Bush, S P Hammar Jr, R H Rudolph |
Journal | Archives of internal medicine
(Arch Intern Med)
Vol. 146
Issue 3
Pg. 503-5
(Mar 1986)
ISSN: 0003-9926 [Print] United States |
PMID | 3954521
(Publication Type: Case Reports, Journal Article)
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Chemical References |
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Topics |
- Administration, Oral
- Adult
- Cyclophosphamide
(therapeutic use)
- Humans
- Male
- Middle Aged
- Pancreatitis
(drug therapy)
- Panniculitis, Nodular Nonsuppurative
(diagnostic imaging, drug therapy, physiopathology)
- Retroperitoneal Neoplasms
(pathology)
- Tomography, X-Ray Computed
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