The use of botulinum toxin in the medical management of benign essential blepharospasm.

Abstract

Twenty-eight patients with mild or moderate cases of benign essential blepharospasm were treated with botulinum toxin Type A. Average follow-up was six months. The injection technique used on these patients is illustrated. The treatment was effective in virtually all patients treated, although transient; the mean interval of relief of spasm was approximately two and one-half months. Potential side effects include ptosis and epiphora. Botulinum toxin as an initial treatment or as an adjunct in postsurgical residual blepharospasm shows promise in this preliminary study.

• Authors: K I Perman, H I Baylis, A L Rosenbaum, D G Kirschen
• Journal: Ophthalmology (Ophthalmology) Vol. 93 Issue 1 Pg. 1-3 (Jan 1986) ISSN: 0161-6420 [Print] United States
• PMID: 3951806 (Publication Type: Journal Article)

Chemical References

• Botulinum Toxins

Topics

• Adult
• Aged
• Blepharospasm (drug therapy)
• Botulinum Toxins (therapeutic use)
• Drug Evaluation
• Eyelid Diseases (drug therapy)
• Female
• Humans
• Male
• Middle Aged
• Prospective Studies