[Vascular invasion, lymph node metastasis and extraglandular extension of well-differentiated carcinoma of the thyroid].

Abstract

Forty-five surgically removed thyroid glands with well-differentiated carcinoma were histologically analyzed to clarify the relationships among vascular invasion, lymph node metastasis and extraglandular extension. Using Victoria blue-HE stain, vascular invasion can be detected as the evident finding of circular elastic fibers surrounding the cancer cluster. In our series, 60% of the subjects were positive for vascular invasion. Patients with vascular invasion tend to show lymph node metastasis and/or extraglandular extension. This correlation was statistically significant. Therefore, in a patient with lymph node metastasis and/or extraglandular extension, there is a greater possibility of vascular invasion being present as well.

• Authors: T Hosoya, A Sakamoto, K Sakurai, N Kasai
• Journal: Gan no rinsho. Japan journal of cancer clinics (Gan No Rinsho) Vol. 32 Issue 1 Pg. 23-6 (Jan 1986) ISSN: 0021-4949 [Print] Japan
• PMID: 3951124 (Publication Type: English Abstract, Journal Article)

Topics

• Adult
• Aged
• Carcinoma (blood supply, pathology)
• Female
• Humans
• Lymphatic Metastasis
• Male
• Middle Aged
• Neoplasm Invasiveness
• Neoplastic Cells, Circulating
• Thyroid Neoplasms (blood supply, pathology)