[Gastric secretion after vagotomy at different levels].

It is well known that all the different procedures of vagotomy have a great variability in the clinical results and a high incidence of positivity in the Hollander's tests, this probably due to the arrangement of the vagus nerves in the low third of the esophagus and its connection with the mienteric plexus. In a group of ten dogs with a gastric fistula we obtained first a sufficient number of assays with vagal stimulation, later on vagotomy was done at the level of the esophago-gastric union (EGU), getting a decrease in the gastric secretion of hydrochloric acid of 64%, afterwards a second section of the vagus nerves was practiced, five centimeters above the EGU having an inhibition of 90% and finally 95% was attained when the vagotomy was done 15 centimeters above the EGU. It is concluded that it is needed a long vagal resection of the last ten centimeters, instead of the classic section of the nerve at the gastroesophagic union; it is the same case with a parietal cell mass vagotomy.
AuthorsF Iñigo Muñoz, L Arellanes, C Sánchez, O Arroyo, C de la Rosa
JournalRevista de gastroenterología de México (Rev Gastroenterol Mex) 1979 Oct-Dec Vol. 44 Issue 4 Pg. 185-94 ISSN: 0375-0906 [Print] MEXICO
Vernacular TitleSecreción gástrica después de vagotomía a diferentes niveles.
PMID394269 (Publication Type: Comparative Study, English Abstract, Journal Article)
Chemical References
  • Insulin
  • Animals
  • Disease Models, Animal
  • Dogs
  • Gastric Juice (secretion)
  • Insulin (pharmacology)
  • Secretory Rate
  • Stimulation, Chemical
  • Stomach (innervation)
  • Stomach Ulcer (surgery)
  • Vagotomy (methods)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!

Choose Username:
Verify Password: